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If you’ve been following health and wellness trends, you’ve likely heard a lot about GLP-1 medications, especially names like semaglutide (commonly known by brand names like Ozempic and Wegovy) and tirzepatide (branded as Mounjaro and Zepbound). These medications have become increasingly popular not only for managing type 2 diabetes but also for their dramatic effects on weight loss. But what are GLP-1s, and how do they actually work in the body?
Let’s break it down.
What Are GLP-1s?
GLP-1 stands for glucagon-like peptide-1, a hormone released in the gut in response to eating. It plays a key role in regulating blood sugar, insulin secretion, and appetite. For individuals with type 2 diabetes or obesity, this system may not work efficiently—and that’s where GLP-1 medications come in.
GLP-1 receptor agonists are medications that mimic the natural hormone, allowing it to remain active in the body longer and deliver powerful health benefits.
How Do GLP-1 Medications Work?
These medications support both blood sugar control and weight loss by targeting multiple systems:
Pancreas
They stimulate insulin release (when blood sugar is high) and reduce glucagon secretion, helping lower blood sugar.
Stomach
They slow gastric emptying, helping you feel fuller longer after meals.
Brain
They affect appetite regulation centers in the brain, reducing hunger and cravings.
Body Weight
By promoting satiety and regulating how the body handles glucose and fat, GLP-1s support sustainable weight loss.
Tirzepatide vs. Semaglutide
Both tirzepatide and semaglutide are powerful tools, but they act slightly differently:
Semaglutide
- A GLP-1 receptor agonist
- Weekly injection (brand names Ozempic for diabetes, Wegovy for weight loss)
- Helps many patients achieve 10–15% weight loss with lifestyle support
Tirzepatide
- Dual-action: mimics GLP-1 and GIP (another metabolic hormone)
- Weekly injection (brand names Mounjaro and Zepbound)
- Some clinical trials show average weight loss of 15–20% or more
Because tirzepatide acts on two hormone pathways, it may have enhanced benefits for blood sugar control and weight reduction.
Are GLP-1 Medications Right for You?
GLP-1s are FDA-approved prescription medications and should be taken under the guidance of a licensed healthcare provider. They’re typically recommended for:
- Individuals with type 2 diabetes
- Adults with a BMI over 30, or over 27 with weight-related medical conditions
- Patients who have not responded well to lifestyle changes alone
Like all medications, GLP-1s can have side effects, including nausea, fatigue, constipation, and more rarely, gastrointestinal issues. That’s why medical oversight is essential.
Final Thoughts: How ACE Ensures Patient Safety
At Aesthetic Center of Excellence, we’re proud to offer GLP-1-based medical weight loss programs using semaglutide and tirzepatide—but we do so with your long-term health and safety in mind.
We don’t take a one-size-fits-all approach. Every patient begins with a thorough consultation, where we assess your health history, lab work, and personal goals. Once therapy begins, we require ongoing lab monitoring throughout your treatment. These labs help us:
- Track your metabolic health and organ function
- Adjust your dose as needed
- Identify and address any side effects early
- Ensure your weight loss is happening in a safe, sustainable way
Your journey with GLP-1 medications at ACE is fully supported by experienced medical providers who prioritize your overall well-being—not just the number on the scale.
If you’re curious whether semaglutide or tirzepatide is right for you, we invite you to book a consultation with our team. We’re here to guide you toward a healthier, more confident you—with the safety, education, and support you deserve.
